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趙 晉 教授
作者:趙晉    編輯:潘彩云     校審: 馮若飛 柏家林 哈玉梅 審簽: 馮若飛 柏家林 哈玉梅     發(fā)布時(shí)間:2024-01-31    訪(fǎng)問(wèn)量:

個(gè)人基本情況:

趙晉,女,教授,博士,博士研究生導(dǎo)師,中國(guó)民族醫(yī)藥協(xié)會(huì)常務(wù)理事,中國(guó)環(huán)境誘變劑學(xué)會(huì)活性氧生物學(xué)效應(yīng)專(zhuān)業(yè)委員會(huì)常委,國(guó)家民委領(lǐng)軍人才和甘肅省青年教師成才獎(jiǎng)獲得者。主要從事DNA損傷和病原微生物致病機(jī)制方面的研究工作。主持國(guó)家自然科學(xué)基金4項(xiàng),主持省部級(jí)科研項(xiàng)目4項(xiàng)。主編和參與編寫(xiě)著作4部。先后在各級(jí)刊物上公開(kāi)發(fā)表論文70余篇,其中SCI收錄論文20余篇。

教育經(jīng)歷:

1986.9-1991.7在西北民族學(xué)院醫(yī)療系學(xué)習(xí);

1997.9-2000.7 在蘭州醫(yī)學(xué)院微生物與免疫學(xué)專(zhuān)業(yè)攻讀碩士學(xué)位;

2000.9-2004.7 在蘭州大學(xué)細(xì)胞生物學(xué)專(zhuān)業(yè)攻讀博士學(xué)位;

2007.1-2008.1 赴加拿大哥倫比亞省癌癥研究中心從事博士后研究。

工作經(jīng)歷:1991年至今在西北民族大學(xué)醫(yī)學(xué)部工作。

科研獎(jiǎng)勵(lì):獲得甘肅省科技進(jìn)步三等獎(jiǎng)2次、甘肅省高??萍歼M(jìn)步一等獎(jiǎng)和三等獎(jiǎng)各1次、甘肅省醫(yī)學(xué)會(huì)科技進(jìn)步三等獎(jiǎng)1次、蘭州市科學(xué)技術(shù)進(jìn)步三等獎(jiǎng)1次、中國(guó)民族醫(yī)藥協(xié)會(huì)科學(xué)技術(shù)進(jìn)步二等獎(jiǎng)1次。

研究生培養(yǎng)情況:培養(yǎng)在讀博士2人,已培養(yǎng)碩士研究生17人。

主要學(xué)術(shù)成果:

1JinZhao, Zhong Guo, Hong Zhang, Zhenhua Wang, LeiSong, Jianxiu Ma, Shuyan Pei, Chenjing Wang. The potential value of the neutralcomet assay and γH2AX foci assay in assessing the radiosensitivity of carbonbeam in human tumor cell lines. RADIOL ONCOL. 2013 ,47(3):247-57.

2Zhong Guo, Jin Zhao(通訊作者) , Lei Song, Jian-Xiu Ma, Chen-Jing Wang,Shu-Yan Pei, Chao Jiang and Shang-Biao Li. Induction of H2AX phosphorylation intumor cells by gossypol acetic acid is mediated by phosphatidylinositol3-kinase (PI3K) family. Cancer Cell International. 2014 ,14:141.doi:10.1186/s12935-014-0141-5.

3ZHONG GUO, SHUYAN PEI, TIANBIN SI, JING LI,CHAO JIANG, SHANGBIAO LI and JIN ZHAO*(通訊作者).Expression of the γ-phosphorylated histone H2AX in gastric carcinoma andgastric precancerous lesions. Oncology Letters .9:1790-1794,2015. DOI: 10.3892/ol.2015.2896

4J.Zhao*,(通訊作者) Q. Wang, J. Li, T.B. Si, S.Y. Pei, Z. Guo,C. Jiang. Comparative study of phosphorylated histone H2AX expressions in thecervical cancer patients of pre- and postneoadjuvant chemotherapy. Eur. J.Gynaecol. Oncol . 2015;36(3):318-22. DOI: 10.12892/ejgo2689.2015

5JinZhao*, Zhong Guo, Qiang Wang, Tianbin Si, ShuyanPei, Chenjing Wang, Hongmei Qu, Jianbin Zhong, Ying Ma, Cong Nie, Dan Zhang.Human papillomavirus genotypes associated with cervical precancerous lesionsand cancer in the highest area of cervical cancer mortality, Longnan, China.Infectious Agents and Cancer 2017;12:8.

6JinZhao*, Zhong Guo, Shuyan Pei, Lei Song, ChenjingWang, Jianxiu Ma, Long Jin, Yanqing Ma, Renke He, Jianbin Zhong, Ying Ma, HongZhang. pATM and γH2AX are effective radiation biomarkers in assessing theradiosensitivity of 12C6+ in human tumor cells. Cancer Cell International. 2017,17:49.

7Fei Zhao· Jin Zhao· Lei Song· YaQing Zhang· Zhong Guo· KeHu Yang. The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa. Apoptosis (2017) 22(11):1461–1472. (SCI)

8JinYing Liu#, Xiaokang Liu, Wei Ma, WeiKou, CaiLi Li, Jin Zhao*(通訊作者).Anticancer activity of cucurbitacin-A in ovarian cancer cell line SKOV3involves cell cycle arrest, apoptosis and inhibition of mTOR/PI3K/Akt signalingpathway. JBUON 2018; 23(1): 124-128.

9Zhao J, Guo Z, Wang Q, Si T, Pei S, Qu H, ShangL, Yang Y, Wang L. HPV infection associated DNA damage correlated with cervicalprecancerous lesions and cancer in the highest area of cervical cancermortality, Longnan, China. Cancer Management and Research. 2019, 11:7197-7210.

10尚立娜; 安利鋒; 張城; 龔川友;周彰映;田世馨;李曉琴;趙晉*(通訊作者).HPV16E7 的表達(dá)對(duì)宮頸癌變過(guò)程中CD163+巨噬細(xì)胞的浸潤(rùn)及上皮間質(zhì)轉(zhuǎn)化的影響, 中國(guó)組織化學(xué)與細(xì)胞化學(xué)雜志, 2019, 28(05): 1-8.

11尚立娜; 周彰映; 張城; 龔川友;田世馨;安利鋒;李曉琴;趙晉*(通訊作者). Bcl2轉(zhuǎn)錄抑制因子1、E-鈣黏蛋白在宮頸鱗狀細(xì)胞癌不同區(qū)域的表達(dá)及兩者與P16INK4a表達(dá)的關(guān)系, 第二軍醫(yī)大學(xué)學(xué)報(bào), 2019,40(12): 1317-1324.

12JinYing Liu#, , Wei Ma, Wei Kou, LinaShang, Rui Huang, Jin Zhao*(通訊作者).Poly-amino acids coated gold nanorod and doxorubicin for synergisticphotodynamic therapy and chemotherapy in ovarian cancer cells. BioscienceReports (2019) 39 BSR20192521.

13Yaqing Zhang, Hongyun Gan, Fei Zhao,Xiaomei Ma, Xiaofeng Xie, Rui Huang, JinZhao*(通訊作者).CPEB4-Promoted Paclitaxel Resistance in Ovarian CancerIn Vitro Relies on Translational Regulation of CSAG2. Front Pharmacol. 2021 Jan13;11:600994.

14宋雷,郭忠,趙玉,李焱,付玉婷,趙晉*(通訊作者).BICC1基因與胃癌進(jìn)展和預(yù)后相關(guān)性的生物信息學(xué)分析, 基因組學(xué)與應(yīng)用生物學(xué), 2021,40(12): 1317-1324.

15Fei Zhao, Zhong Guo, Zhong-Ren Ma, Ling-LiMa, Jin Zhao*(通訊作者).Antitumor activities of Grifola frondosa (Maitake) polysaccharide: Ameta-analysis based on preclinical evidence and quality assessment. Journal ofEthnopharmacology. 2021, 280:114395.

16Fei Zhao, Zhong Guo, Yaqing Zhang, Lei Song, Lingli Ma, Jin Zhao*. Anti-tumor and immunomodulatory effects of Grifola frondosa polysaccharide combined with vitamin C on Heps-bearing mice: Based on inducing apoptosis and autophagy. Journal of Functional Foods. 87 (2021) 104797. (SCI) (通訊作者)

17郭忠,馬建秀,馬艷慶,宋雷,汪晨?jī)?,郭淼,夏溪,趙晉*(通訊作者).蘭州百合多糖片段對(duì)X射線(xiàn)誘導(dǎo)的小鼠骨髓有核細(xì)胞損傷的保護(hù)作用.[J]. 輻射研究與輻射工藝學(xué)報(bào),2022,40(1):010302 (7).  (CSCD核心)

18Zilong Zhang, Linghong Zhu, Yanqing Ma, Bo Wang, Caihong Ci, Jingni Zhang, Yunsong Zhou, Chunjiang Dou, Qiaoling Gu, Yan An, Yongmei Lan, Jin Zhao*. Study on the Characteristics of Intestinal Flora Composition in Gastric Cancer Patients and Healthy People in the Qinghai Tibet Plateau. Applied Biochemistry and Biotechnology. 2022 Apr;194(4):1510-1526. (SCI) (通訊作者)

19Guo Z. Zhu T. Zhou Y. Si T. Wang Q. Qu H. Wang C. Zhao J*.Relationship between Human Papillomavirus Prevalence and DNA Damage in Cervical Cancer Population in Gansu Province, China. Intervirology. 2022;65:215-223.   (SCI) (通訊作者)

20王小恒,李裕,張芳,趙晉*(通訊作者),董開(kāi)忠.氣候變暖與干旱復(fù)合脅迫對(duì)小麥幼苗亞細(xì)胞銅、錳動(dòng)態(tài)積累和分布的影響.[J]. 應(yīng)用與環(huán)境生物學(xué)報(bào),2022, 28 (5): 1239 -1246.

21S Kang#, Z Guo#, F Zhao, L Song, L Lu, C Wang, Z Liu,?and J Zhao?. Lanzhou Lily Polysaccharide Fragment Protects Human Umbilical Vein Endothelial Cells from Radiation-Induced DNA Double Stranded Breaks.Human and Experimental Toxicology. Human & Experimental Toxicology. 2022;41: 1–10. (SCI) (通訊作者)

22Yanqing  Ma,  Caihong  Ci,  Yunsong  Zhou,  Zilong  Zhang, Qiaoling  Gu,  Xiao  Yang,  Fulong  An,  Yan  An,Yongmei  Lan*  and  Jin  Zhao 1,4*.Analysis of gut microbiotal diversity in healthy young adults in Sunan County, Gansu Province, China. Front. Cell. Infect. Microbiol., 2023;13:1-13. (SCI) (通訊作者)

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